(3-Trifluoromethyl-pyrazol-1-yl)-acetic acid
(3-Trifluoromethyl-pyrazol-1-yl)-acetic acid
CAS: 926241-24-9
Molecular Formula: C6H5F3N2O2
(3-Trifluoromethyl-pyrazol-1-yl)-acetic acid - Names and Identifiers
| Name | (3-Trifluoromethyl-pyrazol-1-yl)-acetic acid |
| Synonyms | (3-Trifluoromethyl-pyrazol-1-yl)-acetic acid 2-[3-(Trifluoromethyl)pyrazol-1-yl]acetic acid |
| CAS | 926241-24-9 |
(3-Trifluoromethyl-pyrazol-1-yl)-acetic acid - Physico-chemical Properties
| Molecular Formula | C6H5F3N2O2 |
| Molar Mass | 194.11 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD04969231 |
(3-Trifluoromethyl-pyrazol-1-yl)-acetic acid - Introduction
2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid, also known as (+)-acetic acid, is an organic compound. The properties of the compound are as follows:
1. Appearance: 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid was a colorless crystalline solid.
2. Solubility: The compound is soluble in polar organic solvents, such as alcohols, esters and chlorinated hydrocarbons.
3. Melting point: The melting point of the compound is about 75-77°C.
4. pKa value: The pKa value of this compound was about 4.94.
The use of this compound mainly includes the following aspects:
1. Chemical synthesis: 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid is commonly used as an important intermediate in organic synthesis and is used in the synthesis of other organic compounds.
2. Pesticide: This compound also has application potential in the field of pesticides and can be used to control weeds and pests.
3. Drug research: The compound is an important chemical raw material in drug research and can be used to synthesize biologically active compounds.
The method for preparing 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid mainly includes the following steps:
1. Benzoic acid and chloroacetic anhydride are reacted under alkaline conditions to generate benzoyl acetic acid.
2. benzoyl acetic acid and trifluoromethylcarbamic acid are reacted under acid catalysis to generate 2-[3-(trifluoromethyl)-1H-pyrazol -1-yl] acetic acid.
Regarding the safety information of 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid, the following are general recommendations:
1. toxicity: the toxicity of the compound is low, but should still avoid direct contact or inhalation of its powder or solution. If exposed, rinse immediately with plenty of water and seek medical advice.
2. combustion: avoid contact with the heat source, and stored in a cool, well-ventilated place. Avoid storage with oxidizers and combustibles.
3. Storage Note: The compound should be stored in an airtight container, away from open flames and heat sources.
1. Appearance: 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid was a colorless crystalline solid.
2. Solubility: The compound is soluble in polar organic solvents, such as alcohols, esters and chlorinated hydrocarbons.
3. Melting point: The melting point of the compound is about 75-77°C.
4. pKa value: The pKa value of this compound was about 4.94.
The use of this compound mainly includes the following aspects:
1. Chemical synthesis: 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid is commonly used as an important intermediate in organic synthesis and is used in the synthesis of other organic compounds.
2. Pesticide: This compound also has application potential in the field of pesticides and can be used to control weeds and pests.
3. Drug research: The compound is an important chemical raw material in drug research and can be used to synthesize biologically active compounds.
The method for preparing 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid mainly includes the following steps:
1. Benzoic acid and chloroacetic anhydride are reacted under alkaline conditions to generate benzoyl acetic acid.
2. benzoyl acetic acid and trifluoromethylcarbamic acid are reacted under acid catalysis to generate 2-[3-(trifluoromethyl)-1H-pyrazol -1-yl] acetic acid.
Regarding the safety information of 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl] acetic acid, the following are general recommendations:
1. toxicity: the toxicity of the compound is low, but should still avoid direct contact or inhalation of its powder or solution. If exposed, rinse immediately with plenty of water and seek medical advice.
2. combustion: avoid contact with the heat source, and stored in a cool, well-ventilated place. Avoid storage with oxidizers and combustibles.
3. Storage Note: The compound should be stored in an airtight container, away from open flames and heat sources.
Last Update：2024-04-10 22:39:43
